Example:

If you input a DNA sequence, such as proinsulin:

ATGGGCAGCAGCCATCATCATCATCATCACAGCAGCGGCCTGGATCCGGTGCTGATGTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTACCTAGTGTGCGGAGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGACCTGCAGGTGGGACAGGTGGAGCTGGGCGGAGGCCCTGGTGCAGGCAGCCTGCAGCCCTTGGCCCTGGAGGGATCCCTGCAGAAGCGTGGCATTGTGGAACAATGCTGTACCAGCATCTGCTCCCTCTACCAGCTGGAGAACTACTGCAACTAG

you get the probabilities of high expression and the modified sequences:

>proinsulin-WT,P=0.538187,GC=0.601
ATGGGCAGCAGCCATCATCATCATCATCACAGCAGCGGCCTGGATCCGGTGCTGATGTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTACCTAGTGTGCGGAGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGACCTGCAGGTGGGACAGGTGGAGCTGGGCGGAGGCCCTGGTGCAGGCAGCCTGCAGCCCTTGGCCCTGGAGGGATCCCTGCAGAAGCGTGGCATTGTGGAACAATGCTGTACCAGCATCTGCTCCCTCTACCAGCTGGAGAACTACTGCAACTAG
>proinsulin-AGhead,P=0.618882,GC=0.569
ATGGGAAGTAGTCATCATCATCATCATCATAGTAGTGGATTAGATCCAGTGCTGATGTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTACCTAGTGTGCGGAGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGACCTGCAGGTGGGACAGGTGGAGCTGGGCGGAGGCCCTGGTGCAGGCAGCCTGCAGCCCTTGGCCCTGGAGGGATCCCTGCAGAAGCGTGGCATTGTGGAACAATGCTGTACCAGCATCTGCTCCCTCTACCAGCTGGAGAACTACTGCAACTAG
>proinsulin-AG44G,P=0.882107,GC=0.544
ATGGGAAGTAGTCATCATCACCACCATCACAGCAGCGGTCTCGACCCGGTTCTCATGTTTGTAAACCAGCATCTGTGCGGATCACACCTGGTGGAGGCGCTGTACCTCGTTTGCGGAGAGCGTGGCTTCTTCTATACGCCGAAGACGCGTCGCGAAGCGGAAGACCTCCAAGTTGGCCAAGTGGAACTCGGAGGAGGACCGGGAGCTGGAAGTCTCCAACCGCTGGCGCTCGAGGGAAGTCTCCAGAAACGTGGCATTGTAGAACAGTGCTGCACCAGCATCTGTAGCCTCTATCAACTCGAAAATTATTGTAACTAA
>proinsulin-AG29G,P=0.982975,GC=0.516
ATGGGAAGTAGTCATCATCATCATCATCATTCATCAGGTCTCGATCCGGTACTGATGTTCGTAAACCAACATCTCTGTGGCTCACATCTGGTAGAAGCGCTGTATCTCGTATGCGGTGAACGCGGGTTCTTCTATACCCCGAAGACCCGCCGCGAAGCGGAAGATCTGCAAGTAGGACAAGTAGAACTGGGCGGAGGTCCCGGAGCGGGATCACTCCAACCGCTCGCGCTGGAAGGTAGCCTGCAAAAGCGCGGCATTGTAGAACAATGCTGCACCTCAATTTGCAGCCTGTATCAACTGGAAAACTATTGCAACTAA